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CAS RN: 145572-44-7 | 产品编码: O0505
Sophocarpine Monohydrate
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| 产品编码 | O0505 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__1__5H__2__2N__2O·H__2O = 264.37 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| CAS RN | 145572-44-7 |
| PubChem物质ID | 354335715 |
| MDL编号 | MFCD27923119 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 10.00 to 11.00 % |
| Specific rotation [a]20/D | -23.0 to -27.0 deg(C=1, MeOH) |
| Water | 6.0 to 9.0 % |
| NMR | confirm to structure |
物性（参考值）
| 比旋光度 [α]D | -25° (C=1,MeOH) |
GHS
相关法规
运输信息
| HS编码* | 2939.79-000 |
应用
Sophocarpine: A Tetracyclic Quinolizidine Alkaloid Embracing a Wide Range of Pharmacological Effects
Sophocarpine, a tetracyclic quinolizidine alkaloid, is a major ingredient in Sophora alopecuroides which is one of the important herbal medicines1-3). Sophocarpine has been reported to have a wide range of pharmacological effects4-6). (The product is for research purpose only.)
References
- 1)Determination of quinolizidine alkaloids in traditional Chinese herbal drugs by nonaqueous capillary electrophoresis
- 2)Subcritical water extraction of alkaloids in Sophora flavescens Ait. and determination by capillary electrophoresis with field-amplified sample stacking
- 3)A sensitive and specific HPLC-MS method for the determination of sophoridine, sophocarpine and matrine in rabbit plasma
- 4)Antiviral Chinese medicinal herbs against respiratory syncytial virus
- 5)(+)-12α-Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescens
- 6)Sophocarpine and matrine inhibit the production of TNF-α and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice
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