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CAS RN: 59-67-6 | 产品编码: N0082
Nicotinic Acid
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| 规格 | 单价 | 同一天 | 2-3个工作日 | 数量 |
|---|---|---|---|---|
| 25G |
S$28.50
|
36 | ≥100 |
|
| 500G |
S$88.50
|
4 | ≥80 |
|
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 99.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
| Melting point | 235.0 to 240.0 °C |
| Solubility in hot Water | almost transparency |
物性（参考值）
| 熔点 | 238 °C |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | QT0525000 |
运输信息
| HS编码* | 2936.29-000 |
应用
ニコチン酸の三つの面：ビタミンB3，抗高脂血症剤，および配位高分子化合物の架橋リガンド
Nicotinic acid has three faces. The first is vitamin B3 (called niacin) which is required for the synthesis of coenzymes, nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP).1) The second is an antilipemic agent which acts on the nicotinic acid receptor, inhibiting the enzyme triglyceride lipase.2-4) The last is a bridging ligand for coordination polymers which is used for the synthesis of MOF/PCP.5) For your reference, we have its analogue, acipimox [M2053]. (The product is for research purpose only.)
References
- 1)Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition (a review)
- 2)Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review
- 3)Mechanism of action of niacin
- 4)Nicotinic acid: pharmacological effects and mechanisms of action (a review)
- 5)Novel 3-D Framework Nickel(II) Complex with Azide, Nicotinic Acid, and Nicotinate(1-) as Coligands: Hydrothermal Synthesis, Structure, and Magnetic Properties
参考文献
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![Nicotinic Acid [Matrix for MALDI-TOF/MS]](/medias/N1103.jpg?context=bWFzdGVyfHJvb3R8MzIyMDB8aW1hZ2UvanBlZ3xhRGRoTDJoa05pODRPVE14TnpRNU56STBNVGt3TDA0eE1UQXpMbXB3Wnd8NDAxYjhhNTQ2ZmJjNTMxYTRlNTc4OGYzODViZTI0MmYyNDNmMGY5MjI5NjdhZDIzZDUzZGQ0ZGEyNjY2MDc3Zg "Nicotinic Acid [Matrix for MALDI-TOF/MS]")