Maximum quantity allowed is 999
请选择数量
CAS RN: 19457-55-7 | 产品编码: M3121
6-Methyleneandrost-4-ene-3,17-dione
×
![]()
×
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +390 to +430 deg(C=1, CHCL3) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 164 °C(dec.) |
| 比旋光度 [α]D | 411° (C=1,CHCl3) |
| 最大吸收波长 | 259(EtOH) nm |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H361 : Suspected of damaging fertility or the unborn child. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相关法规
运输信息
| HS编码* | 2937.90-000 |
应用
A Synthetic Intermediate of Exemestane
This product is a synthetic intermediate of exemestane (FCE 24304) [E0941] which is a potent and selective aromatase inhibitor.
References
- 6-Methylenandrosta-1,4-diene-3,17-dione (FCE 24304): a new irreversible aromatase inhibitor
- Synthesis and aromatase inhibition by potential metabolites of exemestane (6-methylenandrosta-1,4-diene-3,17-dione)
- 1,2-Dehydrogenation of steroidal 6-methylene derivatives. Synthesis of exemestane
- Development and validation of a stability indicating LC method for the assay and related substances determination of Exemestane, an aromatase inhibitor
参考文献