Maximum quantity allowed is 999
请选择数量
CAS RN: 12650-69-0 | 产品编码: M2955
Mupirocin
| 产品编码 | M2955 |
| 纯度/分析方法 | >98.0%(T) |
| 分子式/分子量 | C__2__6H__4__4O__9 = 500.63 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (<0°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,湿气 (吸湿),加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片）, 25MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 12650-69-0 |
| Reaxys-RN | 4726470 |
| PubChem物质ID | 354334600 |
| Merck Index (14) | 6302 |
| MDL编号 | MFCD01711620 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 92.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -18.0 to -21.0 deg(C=1,MeOH) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 78 °C |
| 比旋光度 [α]D | -19° (C=1,MeOH) |
| 最大吸收波长 | 222(EtOH) nm |
GHS
相关法规
| RTECS# | RA6907000 |
运输信息
| HS编码* | 2941.90-000 |
应用
RNA合成酵素を阻害する抗生物質，ムピロシン
Mupirocin is a polyketide antibiotic produced by fermentation using the organism Pseudomonas fluorescens. Mupirocin is fungicidally active against a wide range of Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA). Mupirocin is also active against certain Gram-negative bacteria. Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase. Due to its mode of action, mupirocin does not demonstrate cross resistance with other classes of antibiotic agents. The calcium salt of mupirocin is used as an ointment to control the carriage of MRSA on skin and in nasal passages as well as for various skin infections. Recently, mupirocin resistance in Staphylococcus aureus is increasingly being reported in many parts of the world. (The product is for research purpose only.)
References
- Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid
- Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use
- Mupirocin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use (a review)
- Insights into editing from an Ile-tRNA synthetase structure with tRNAIle and mupirocin
- Mupirocin resistance (a review)
- Resistance to and synthesis of the antibiotic mupirocin (a review)
- Development and validation of RP-HPLC method for simultaneous estimation of prednicarbate, mupirocin and ketoconazole in topical dosage forms
参考文献
文章/手册
TCIMail
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。