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CAS RN: 108612-45-9 | 产品编码: M2756
Mizolastine
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| 产品编码 | M2756 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__2__4H__2__5FN__6O = 432.50 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 108612-45-9 |
| Reaxys-RN | 7259331 |
| PubChem物质ID | 253661171 |
| Merck Index (14) | 6221 |
| MDL编号 | MFCD23140913 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 222.0 to 226.0 °C |
物性（参考值）
| 熔点 | 224 °C |
| 溶解性（可溶于） | 甲醇 |
GHS
相关法规
| RTECS# | UW7481284 |
运输信息
| HS编码* | 2933.99-000 |
应用
ヒスタミンH1-受容体アンタゴニスト，ミゾラスチン
Mizolastine is a histamine H1-receptor antagonist with no anticholinergic, antiadrenergic, or antiserotonin activity. It is used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. (The product is for research purpose only.)
References
- In vivo and in vitro interaction of the novel selective histamine H1 receptor antagonist mizolastine with H1 receptors in the rodent
- Anti-anaphylactic activity of the novel selective histamine H1 receptor antagonist mizolastine in the rodent
- Anti-inflammatory properties of mizolastine after oral administration on arachidonic acid-induced cutaneous reaction in the rat
- Comparison of pharmacokinetics and metabolism of desloratadine [D3787], fexofenadine [F0698], levocetirizine [L0264] and mizolastine in humans (a review)
- Determination of mizolastine, a new antihistaminic drug, in human plasma by liquid-liquid extraction, solid-phase extraction and column-switching techniques in combination with high-performance liquid chromatography
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