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CAS RN: 2444-46-4 | 产品编码: M0900
N-Vanillylnonanamide [=Capsaicin (Synthetic)]
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![N-Vanillylnonanamide [=Capsaicin (Synthetic)]](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "N-Vanillylnonanamide [=Capsaicin (Synthetic)]")
技术规格
| Appearance | White to Light yellow to Light orange powder to lump |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 52.0 to 62.0 °C |
物性（参考值）
| 熔点 | 54 °C |
| 溶解性（可溶于） | 氯仿 |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H300 : Fatal if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H335 : May cause respiratory irritation. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相关法规
| RTECS# | RA5955000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | II |
| HS编码* | 2924.29-000 |
应用
Reagent for pain model
References
- Activation of the cAMP transduction cascade contributes to the mechanical hyperalgesia and allodynia induced by intradermal injection of capsaicin
- Stimulation of deep somatic tissue with capsaicin produces long-lasting mechanical allodynia and heat hypoalgesia that depends on early activation of the cAMP pathway
- Comparison of antinociceptive actions of standard analgesics in attenuating capsaicin and nerve-injury-induced mechanical hypersensitivity
- Increased spinal release of excitatory amino acids following intradermal injection of capsaicin is reduced by a protein kinase G inhibitor
- Role of protein kinase A in phosphorylation of NMDA receptor 1 subunits in dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats
- Capsaicin-induced sensitization of primate spinothalamic tract cells is prevented by a protein kinase C inhibitor
- Inhibitors of G-proteins and protein kinases reduce the sensitization to mechanical stimulation and the desensitization to heat of spinothalamic tract neurons induced by intradermal injection of capsaicin in the primate
- A new model of visceral pain and referred hyperalgesia in the mouse
应用
Reagent for coughing model
References
- Mechanisms of capsaicin- and citric-acid-induced cough reflexes in guinea pigs
- Animal models of cough: literature review and presentation of a novel cigarette smoke-enhanced cough model in the guinea-pig
- Dynamic modelling of a challenge-escalation cross-over study of treatment of capsaicin-induced coughing
应用
Reagent for acute inflammatory (ear edema) model
Reference
- Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema
参考文献
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技术规格
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