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CAS RN: 6150-58-9 | 产品编码: L0319
Lycorine Hydrochloride Monohydrate
×
纯度/分析方法: >98.0%(T)(HPLC)
别名：
- 盐酸石蒜碱 一水合物
- (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-六氢-1H-[1,3]二氧戊环并[4,5-j]吡咯并[3,2,1-de]菲啶-1,2-二醇盐酸盐 一水合物
- (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol Hydrochloride Monohydrate
产品文档：
| 产品编码 | L0319 |
纯度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__6H__1__7NO__4·HCl·H__2O = 341.79 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
100MG-Glass Bottle with Plastic Insert （查看图片）, 25MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 6150-58-9 |
| 相关CAS RN
|
2188-68-3 |
| Reaxys-RN | 6105700 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +41.0 to +45.0 deg(C=2.9, water) |
| Water | max. 7.0 % |
物性（参考值）
| 熔点 | 215 °C(dec.) |
| 比旋光度 [α]D | 43° (C=2.9,H2O) |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | OL2910000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2934.99-000 |
应用
Lycorine Hydrochloride: The Major Bioactive Alkaloid Found in Amaryllidaceae Family Plant
Lycorine hydrochloride is the major bioactive alkaloid found in Amaryllidaceae family plant, a represent traditional Chinese medicinal herb. Lycorine and its derivatives have been shown to have various biological activities, including anti-leukemia, anti-tumor, anti-angiogenesis, anti-virus, anti-bacteria, anti-inflammation, and anti-malaria. They also exert many biological functions, such as inhibition of acetylcholinesterase. (The product is for research purpose only.)
References
- Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure-Activity Relationship and Mechanistic Insight
- Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives (a review)
- Lycorine and its derivatives for anticancer drug design (a review)
- Multiple biological functions and pharmacological effects of lycorine (a review)
- LCMS and GCMS for the screening of alkaloids in natural and in vitro extracts of Leucojum aestivum
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