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CAS RN: 226721-96-6 | 产品编码: L0252
Loxoprofen Sodium Salt Dihydrate
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Ion exchange titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | 11.0 to 13.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 198 °C(dec.) |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | CY1678845 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2918.30-000 |
应用
Studies on Nonsteroidal Antiinflammatory Agents
References
- Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells
- Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-sodium, an anti-inflammatory prodrug
- Inhibition of prostaglandin synthesis by sodium 2-[4-(2-oxocyclopentylmethyl)phenyl] propionate dihydrate (CS-600), a new antiinflammatory drug, and its active metabolite in vitro and in vivo
- Purification and some properties of ketone reductase forming an active metabolite of sodium 2-[4-(2-oxocyclopentylmethyl)phenyl]propionate dihydrate (loxoprofen sodium), a new antiinflammatory agent, in rabbit liver cytosol
- Identification of degradation products in loxoprofen sodium adhesive tapes by liquid chromatography-mass spectrometry and dynamic pressurized liquid extraction-solid-phase extraction coupled to liquid chromatography-nuclear magnetic resonance spectroscopy
参考文献
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