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CAS RN: 480-19-3 | 产品编码: I1068
Isorhamnetin
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| 产品编码 | I1068 |
纯度/分析方法 
|
>95.0%(HPLC) |
| 分子式/分子量 | C__1__6H__1__2O__7 = 316.27 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
50MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 480-19-3 |
| Reaxys-RN | 44723 |
| PubChem物质ID | 468592077 |
| MDL编号 | MFCD00017310 |
技术规格
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
物性（参考值）
| 最大吸收波长 | 370 nm (MeOH) |
GHS
相关法规
| RTECS# | LK9275450 |
运输信息
| HS编码* | 2932.99-000 |
应用
Efflux pump research
Isorhamnetin has been reported to inhibit efflux pump thereby decreasing the minimum inhibitory concentrations (MICs) of Isoniazid [I0138] against Mycobacterium.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Modulation of isoniazid susceptibility by flavonoids in Mycobacterium
- Effect of naturally occurring flavonoids on lipid peroxidation and membrane permeability transition in mitochondria
- Antioxidant activity and phenolic compounds in 32 selected herbs
- Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κB activation along with their inhibitory effect on iNOS expression and NO production inactivated macrophages
- O-methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation
- In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells
- Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD
应用
Isorhamnetin: A 3'-O-Methylated Flavonoid with Biological Activities
Isorhamnetin is a natural 3'-O-methylated flavonoid (3’-O-methylated quercetin [P0042]) that occurs in fruits and medicinal herbs. It has been investigated in its antioxidant1,2) and anti-inflammatory3,4) activity, and its influence on human cancer cells.5) (The product is for research purpose only.)
References
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技术规格
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