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CAS RN: 22465-48-1 | 产品编码: H1542
Hydroxocobalamin Acetate
产品编码 | H1542 |
纯度/分析方法 | >90.0%(HPLC) |
分子式/分子量 | C__6__4H__9__1CoN__1__3O__1__6P = 1,388.41 |
外观与形状(20°C) | 固体 |
储存温度 | 冷藏 (0-10°C) |
储存在惰性气体下 | 存放于惰性气体之中 |
应避免的情况 | 空气,加热 |
包装和容器 | 1G-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 22465-48-1 |
Reaxys-RN | 19236547 |
PubChem物质ID | 253661238 |
Merck Index (14) | 4809 |
MDL编号 | MFCD00082532 |
技术规格
Appearance | Orange to Brown to Dark red powder to crystal |
Purity(HPLC) | min. 90.0 area% |
Purity(Chelometric Titration) | min. 95.0 %(calcd.on dried substance) |
Drying loss | max. 12.0 % |
物性(参考值)
最大吸收波长 | 350(AcOH buffer Sol. pH4.5) nm |
溶解性(不溶于) | 乙醚 |
GHS
相关法规
RTECS# | GG3740000 |
运输信息
HS编码* | 2936.26-000 |
应用
Hydroxocobalamin Acetate: Long Acting Vitamin B12 Physiological Equivalent Form
Vitamin B12 exists in four major physiological equivalent forms referred to collectively as cobalamins; hydroxocobalamin acetate, cyanocobalamin [C0449], methylcobalamin [M2742], and 5’-deoxyadenosylcobalamine. An intramuscular injection of hydroxocobalamin acetate produces higher serum levels than the same dose of cyanocobalamin, and these levels are well maintained. Cobalamins function as a coenzyme in a number of reactions, including the oxidation of fatty acids and the synthesis of DNA. They also works in conjugation with folic acid [F0043] (Vitamin B9) in the synthesis of the amino acid L-methionine [M0099] and it required for normal production of red blood cells. Although cobalamins are necessary for nervous system maintenance, the mechanisms are not entirely known. Cobalamins can be used to prevent or treat pathology arising from a lack of vitamin B12. (The product is for research purpose only.)
References
- Differential effects of hydroxocobalamin on NO-mediated relaxations in rat aorta and anococcygeus muscle
- Differential effects of hydroxocobalamin on relaxations induced by nitrosothiols in rat aorta and anococcygeus muscle
- Hematopoietic Vitamins with Special Reference to Vitamin B12 and Folic Acid in Clinical Field
- H. Uchino, Acta Haemat. Jpn. 1966, 29, 491.
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