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CAS RN: 210353-53-0 | 产品编码: G0617
Gemifloxacin Mesylate
×
纯度/分析方法: >95.0%(HPLC)(qNMR)
别名：
- 甲磺酸吉米沙星
- 7-[(4Z)-3-(氨基甲基)-4-(甲氧基亚氨基)-1-吡咯烷基]-1-环氧丙基-6-氟-4-氧代-1,4-二氢-1,8-二氮杂萘-3-甲酸甲磺酸盐
- 7-[(4Z)-3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate
产品文档：
| 规格 | 单价 | 同一天 | 2-3个工作日 | 左侧以上货期 | 数量 |
货期信息
|
|---|---|---|---|---|---|---|
| 10MG |
S$178.50
|
8 | 20 | 下单后约2周内可以发货 |
|
| 产品编码 | G0617 |
纯度/分析方法 
|
>95.0%(HPLC)(qNMR) |
| 分子式/分子量 | C__1__8H__2__0FN__5O__4·CH__4O__3S = 485.49 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,加热 |
| CAS RN | 210353-53-0 |
| Reaxys-RN | 8887755 |
| MDL编号 | MFCD08277637 |
技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
物性（参考值）
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H317 : May cause an allergic skin reaction. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
| RTECS# | QN2790988 |
运输信息
| HS编码* | 2933.99-000 |
应用
Gemifloxacin Mesylate: An Orally Active Broad-Spectrum Respiratory Quinolone Antibiotic
Gemifloxacin mesylate (LB20304) is an orally active broad-spectrum fluoroquinolone antibiotic. Fluoroquinolones, including gemifloxacin, inhibit DNA synthesis by inhibiting DNA gyrase and topoisomerase IV activities.1-3) The newest fluoroquinolones, such as gemifloxacin, gatifloxacin [G0627] and moxifloxacin [M2479], are known to have excellent in vitro activity against a wide range of respiratory pathogens and many aerobic Gram-negative organisms.3) (The product is for research purpose only.)
References
- 1) Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines: Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl -6-fluoro- 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304)
- 2) Gemifloxacin (a review)
- 3) Gatifloxacin, gemifloxacin, and moxifloxacin: the role of 3 newer fluoroquinolones (a review)
- 4) Reverse phase-HPLC and HPTLC methods for determination of gemifloxacin mesylate in human plasma
- 5) Determination of gemifloxacin in different tissues of rat after oral dosing of gemifloxacin mesylate by LC-MS/MS and its application in drug tissue distribution study
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