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CAS RN: 23256-50-0 | 产品编码: G0456
Guanabenz Acetate
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| 产品编码 | G0456 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__8H__8Cl__2N__4·C__2H__4O__2 = 291.13 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 应避免的情况 | 光 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片）, 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 23256-50-0 |
| 相关CAS RN | 5051-62-7 |
| Reaxys-RN | 4169995 |
| PubChem物质ID | 253660672 |
| Merck Index (14) | 4558 |
| MDL编号 | MFCD00153801 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 188.0 to 192.0 °C |
物性（参考值）
| 熔点 | 190 °C |
| 水溶性 | 微溶 |
| 在水中的溶解度 | 11 g/l 25 °C |
| 溶解性（可溶于） | 醇 |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | MF0382000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2928.00-000 |
应用
Guanabenz Acetate: A Centrally Acting α2-Adrenergic Receptor Agonist
Guanabenz acetate is a centrally acting α2-adrenergic receptor agonist with low affinity for I1-imidazoline receptors. In mild to moderate hypertension, guanabenz is as effective as methyldopa [D1817] and clonidine [D1353] in lowering blood pressure. (The product is for research purpose only.)
References
- Studies on the centrally mediated hypotensive activity of guanabenz
- Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension
- Guanabenz acetate (a review)
- Alpha-2 Adrenergic Receptor Agonists Block Stress-Induced Reinstatement of Cocaine Seeking
- Centrally acting antihypertensive agents: an update (a review)
参考文献
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