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CAS RN: 16320-04-0 | 产品编码: G0436
Gestrinone
| 规格 | 单价 | 同一天 | 2-3个工作日 | 数量 |
|---|---|---|---|---|
| 100MG |
S$286.50
|
11 | 1 |
|
技术规格
| Appearance | Light yellow to Yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 150.0 to 154.0 °C |
| Specific rotation [a]20/D | +83.0 to +86.0 deg(C=0.4, EtOH) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 152 °C |
| 比旋光度 [α]D | 85° (C=0.4,EtOH) |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H361 : Suspected of damaging fertility or the unborn child. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相关法规
| RTECS# | JF7964000 |
运输信息
| HS编码* | 2937.29-000 |
应用
Gestrinone: A Steroid Hormone with Anti-Estrogenic and Anti-Progesterone Properties
Gestrinone is a synthetic steroid hormone with anti-estrogenic and anti-progesterone properties. It is used to treat endometriosis, shrink uterine fibroids and reduce menorrhagia. Besides, it is investigated for use as emergency contraceptive. Also, due to its anabolic effects, it was included in the banned list of performance enhanced drugs in sport. Therefore, the effective detection of gestrinone and its metabolites in human urine has been studied. (The product is for research purpose only.)
References
- Gestrinone (R2323) binding to steroid receptors in human uterine endometrial cytosol
- Individual and combined effects of triptorelin and gestrinone on experimental endometriosis in rats
- Endometriosis: current therapies and new pharmacological developments (a review)
- Screening for unknown synthetic steroids in human urine by liquid chromatography-tandem mass spectrometry
- Discovery, Biosynthesis, and Structure Elucidation of Metabolites of a Doping Agent and a Direct Analogue, Tetrahydrogestrinone and Gestrinone, Using Human Hepatocytes
- Analysis of synthetic 19-norsteroids trenbolone, tetrahydrogestrinone and gestrinone by gas chromatography-mass spectrometry
参考文献
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