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CAS RN: 73151-29-8 | 产品编码: F1008
Fenticonazole Nitrate
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| 产品编码 | F1008 |
| 纯度/分析方法 | >97.0%(HPLC) |
| 分子式/分子量 | C__2__4H__2__0Cl__2N__2OS·HNO__3 = 518.41 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 73151-29-8 |
| 相关CAS RN | 72479-26-6 |
| PubChem物质ID | 253661427 |
| Merck Index (14) | 4005 |
| MDL编号 | MFCD00941391 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Melting point | 133.0 to 137.0 °C |
物性（参考值）
| 熔点 | 135 °C |
GHS
相关法规
| RTECS# | NI4780000 |
运输信息
| HS编码* | 2933.29-000 |
应用
Fenticonazole Nitrate: An Imidazole Antifungal Agent
Fenticonazole nitrate is an imidazole antifungal agent with a broad spectrum of antimycotic activity against dermatophytes and yeasts. The main mechanism of action of fenticonazole is based on the inhibition of the synthesis of aspartic protease, a virulence enzyme of fungus. Fenticonazole has activity against Gram-positive bacteria, but no activity against Gram-negative bacteria. Fenticonazole used as a racemic mixture in therapy. (The product is for research purpose only.)
References
- Physicochemical, structural and analytical studies on fenticonazole, a new drug with antimycotic properties
- Comparison of the in vitro activities of fenticonazole, other imidazoles, metronidazole, and tetracycline against organisms associated with bacterial vaginosis and skin infections
- In vitro activity of sertaconazole, fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole against pathogenic vaginal yeast isolates
- Topical fenticonazole in dermatology and gynaecology: current role in therapy (a review)
- HPLC analysis of imidazole antimycotic drugs in pharmaceutical formulations
- Chiral discrimination by HPLC and CE and antifungal activity of racemic fenticonazole and its enantiomers
参考文献
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