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CAS RN: 58306-30-2 | 产品编码: F0922
Febantel
产品编码 | F0922 |
分子式/分子量 | C__2__0H__2__2N__4O__6S = 446.48 |
外观与形状(20°C) | 固体 |
储存温度 | 室温 (15°C以下阴凉干燥处) |
包装和容器 | 1G-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 58306-30-2 |
Reaxys-RN | 13258677 |
PubChem物质ID | 253661507 |
Merck Index (14) | 3944 |
MDL编号 | MFCD01738527 |
技术规格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(with Total Nitrogen) | min. 98.0 % |
Melting point | 125.0 to 129.0 °C |
物性(参考值)
熔点 | 130 °C |
水溶性 | 不溶 |
GHS
相关法规
RTECS# | FB3955000 |
运输信息
HS编码* | 2930.90-900 |
应用
Febantel: A Broad-Spectrum Pro-Benzimidazole Anthelminthic
Febantel is a veterinary anthelmintic belonging to the chemical class of the benzimidazoles, but is a so-called pro-benzimidazole. Febantel itself has no anthelmintic properties. It is transformed into active fenbendazole and fenbendazole sulfoxide (= oxfendazole) in the host's liver. It is highly active against various species of nematodes and cestodes in mice, rats, dogs, sheep, and cattle. Recently, Febantel is often used in combination with other anthelmintics (pyrantel pamoate and etc.). (The product is for research purpose only.)
References
- Febantel, a new broad-spectrum anthelminthic
- H. Wollweber, H. Koelling, A. Widdig, H. Thomas, H. P. Schulz, P. Muermann, Arzneim.-Forsch. 1978, 28, 2193.
- In vitro febantel transformation by sheep and cattle ruminal fluids and metabolism by hepatic subcellular fractions from different animal species
- Efficacy of a drug combination of praziquantel, pyrantel pamoate, and febantel against giardiasis in dogs
- S. C. Barr, D. D. Bowman, M. F. Frongillo, S. L. Joseph, Am. J. Vet. Res. 1998, 59, 1134.
- Rapid determination of the antiparasitic drugs flubendazole and febantel in feeds by HPLC with ultraviolet detection
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