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CAS RN: 1405-10-3 | 产品编码: F0649
Fradiomycin Sulfate
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This product has not been tested for potency and is guaranteed for chemical purity.
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(with Total Nitrogen) | min. 97.0 %(calcd.on dried substance) |
| Specific rotation [a]20/D | +55.0 to +61.0 deg(C=10, H2O)(calcd.on dried substance) |
| Drying loss | max. 8.0 % |
物性（参考值）
| 比旋光度 [α]D | 56° (C=10,H2O) |
| 水溶性 | 可溶 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H317 : May cause an allergic skin reaction. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
| RTECS# | QP4375000 |
运输信息
| HS编码* | 2941.90-000 |
应用
RNA aptamer research
References
- Recognition of a cognate RNA aptamer by neomycin B: quantitative evaluation of hydrogen bonding and electrostatic interactions
- A novel RNA motif for neomycin recognition
应用
Fradiomycin or Neomycin: A Broad Spectrum Aminoglycoside Antibiotic
Fradiomycin or neomycin, an aminoglycoside antibiotic, is first isolated in 1949 from the gram-positive bacillus Streptomyces fradiae. It consists of a mixture of two isomers, fradiomycin B and fradiomycin C. Fradiomycin has broad activity against Gram-negative bacteria except Pseudomonas aeruginosa and Gram-positive bacteria. It binds with bacterium ribosome 30s, and then it inhibits bacterial growth by inhibiting protein synthesis.
References
- Neomycin
- Aminoglycoside antibiotics: structure, functions and effects on in vitro plant culture and genetic transformation protocols
- Aminoglycoside-nucleic acid interactions: the case for neomycin
- Antimicrobial agents. Part II. The aminoglycosides. Streptomycin, kanamycin, gentamicin, tobramycin, amikacin, neomycin
- N. S. Brewer, Mayo Clin. Proc. 1977, 52, 675.
参考文献
TCIMail
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