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CAS RN: 490-46-0 | 产品编码: E1226
(-)-Epicatechin
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| 产品编码 | E1226 |
纯度/分析方法 
|
>97.0%(HPLC) |
| 分子式/分子量 | C__1__5H__1__4O__6 = 290.27 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 490-46-0 |
| Reaxys-RN | 92760 |
| PubChem物质ID | 468591690 |
| MDL编号 | MFCD00075648 |
技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | -56.0 to -64.0 deg(C=0.1, MeOH) |
物性（参考值）
| 熔点 | 240 °C(dec.) |
| 比旋光度 [α]D | -62° (C=0.1,MeOH) |
| 最大吸收波长 | 280 nm (MeOH) |
| 溶解性（可溶于） | 甲醇 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | K3745000 |
运输信息
| HS编码* | 2932.99-000 |
应用
Efflux pump research
(-)-Epicatechin has been reported to inhibit efflux pump thereby decreasing the minimum inhibitory concentrations (MICs) of Isoniazid [I0138] against Mycobacterium.1)
（The product is for research purpose only.)
（The product is for research purpose only.)
Reference
- 1) Modulation of isoniazid susceptibility by flavonoids in Mycobacterium
- Determination of Tea Components with Antioxidant Activity
- Metabolism of green tea catechins: an overview
- Green tea extract: Chemistry, antioxidant properties and food applications - A review
- Antiviral effect of catechins in green tea on influenza virus
- Green Tea: Nature's Defense against Malignancies (a review)
- Biological functions of epicatechin: Plant cell to human cell health (a review)
- (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
- Metabolism of green tea catechins: an overview
- Dietary flavonoids: Role of (-)-epicatechin and related procyanidins in cell signaling (a review)
应用
(-)-Epicatechin: A Components of Green Tea with a Variety of Biological Activities
(-)-Epicatechin and (-)-epicatechin gallate [E0890] are major components of green tea which is the most popular beverages worldwide. It has been reported that they possess a variety of biological activities, including antioxidant, anti-inflammatory, antiviral and anti-cancerous properties. (The product is for research purpose only.)
References
应用
(-)-Epicatechin: An Antioxidant Flavonoid with Many Bioactive Properties
(-)-Epicatechin is a flavan-3-ol, an antioxidant flavonoid that is present in green teas, red wine, cocoa products, and many fruits, such as apples. It has demonstrated strong antioxidative, anti-inflammatory and anti-cancerous properties. (The product is for research purpose only.)