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CAS RN: 57-87-4 | 产品编码: E0018
Ergosterol
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技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 156.0 to 162.0 °C |
| Specific rotation [a]20/D | -100 to -125 deg(C=1, THF)(calcd.on anh.substance) |
| Absorbance | min. 0.500(20 mg/L, 269.0 to 273.0 nm) |
| Absorbance2 | min. 0.530(20 mg/L, 280.0 to 284.0 nm) |
| Water | max. 7.0 % |
物性（参考值）
| 熔点 | 159 °C |
| 沸点 | 250 °C/0.01 mmHg |
| 比旋光度 [α]D | -113° (C=1,THF) |
GHS
相关法规
运输信息
| HS编码* | 2936.90-000 |
应用
Ergosterol: A Sterol Found in Cell Membranes of Fungi
Ergosterol is a sterol found in cell membranes of fungi which use principally it instead of cholesterol [C0318] on humans and other mammals. So many antifungal agents target ergosterol as a way to disrupt the fungal plasma membrane. Ergosterol is also called provitamin D2 because exposure it to ultraviolet (UV) light causes a chemical reaction that produces vitamin D2 (calciferol or ergocalciferol) [C0005].
References
- The biosynthesis of ergosterol (a review)
- Ergosterol content in various fungal species and biocontaminated building materials
- The biology and chemistry of antifungal agents: A review
- A new mechanistic scenario for the photochemical transformation of ergosterol: an MC-SCF and MM-VB [molecular mechanics-VB] study
- Sterol and vitamin D2 concentrations in cultivated and wild grown mushrooms: Effects of UV irradiation
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