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CAS RN: 3416-05-5 | 产品编码: D6100
3'-Deoxythymidine
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| 产品编码 | D6100 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__0H__1__4N__2O__4 = 226.23 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气 |
| 包装和容器 | 250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 3416-05-5 |
| Reaxys-RN | 21884 |
| MDL编号 | MFCD00010570 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 152.0 to 156.0 °C |
| Specific rotation | +14.0 to +18.0 deg(C=0.6, water) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 154 °C |
GHS
相关法规
运输信息
| HS编码* | 2934.99-000 |
应用
3'-Deoxythymidine: A Thymidine Analog with Antiviral Activity
3'-Deoxythymidine (2',3'-dideoxythymidine) is a thymidine analog that has antiviral activity. There are reports that it inhibits HIV replication in vitro. (The product is for research purpose only.)
References
- Both 2',3'- dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro
- Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine
- Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs
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技术规格
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