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CAS RN: 638-94-8 | 产品编码: D5578
Desonide
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| 产品编码 | D5578 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__2__4H__3__2O__6 = 416.51 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 光,加热 |
| 包装和容器 | 250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 638-94-8 |
| Reaxys-RN | 56987 |
| PubChem物质ID | 468591424 |
| Merck Index (14) | 2928 |
| MDL编号 | MFCD00866151 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +130 to +134 deg(C=0.5, DMF) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 275 °C |
| 比旋光度 [α]D | 132° (C=0.5,DMF) |
| 最大吸收波长 | 242 nm (MeOH) |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | TU2800000 |
运输信息
| HS编码* | 2937.90-000 |
应用
Desonide: A Low-Potency and Mild Nonfluorinated Topical Corticosteroid
Desonide (prednacinolone) is a low-potency and mild nonfluorinated topical corticosteroid. Its ointment-like preparations have been used widely as a topical treatment for inflammatory dermatoses. (The product is for research purpose only.)
References
- Desonide: a review of formulations, efficacy and safety
- Desonide hydrogel: advances in vehicle technology (a review)
- Development of an HPLC Assay Methodology for a Desonide Cream with Chemometrics Assisted Optimization
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