Maximum quantity allowed is 999
请选择数量
CAS RN: 1091-85-6 | 产品编码: D5406
Dansylglycine [for Albumin binding assay]
×
![]()
×
![Dansylglycine [for Albumin binding assay]](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "Dansylglycine [for Albumin binding assay]")
| 规格 | 单价 | 同一天 | 2-3个工作日 | 数量 |
|---|---|---|---|---|
| 25MG |
S$75.00
|
16 | 18 |
|
| 100MG |
S$225.00
|
24 | 1 |
|
技术规格
| Appearance | Light yellow to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 156.0 to 161.0 °C |
| Human serum albmin (HSA) binding activity | S/N ratio min. 8 |
| Competitive avtivity in competitive drug | Remaining fluorescein inensity max. 30 % |
| Non-competitive avtivity in non-competitive drug | Remaining fluoresein intensity min. 80 % |
物性（参考值）
| 熔点 | 159 °C |
GHS
相关法规
运输信息
| HS编码* | 2935.90-000 |
应用
Fluorescent Probes for the Characterization of Two Specific Drug Binding Sites on HSA
Human Serum Albumin (HSA) binds to a wide variety of drugs at two primary binding sites (I: blue and II: yellow), and can have a significant impact on their pharmacokinetics and pharmacological effects. The fluorescent probes, dansylamide (1) and dansylglycine (2) selectively interact with sites I and II, respectively.1,2) BD140 (3) also binds to drug binding site II specifically.3) Changes in probe fluorescence are analyzed by fluorescence titrations as a result of competitive displacement by drugs and pharmaceuticals. The pattern of fluorescent probe displacement by these reagents enabled the identification of two specific drug binding sites, which illustrates their usefulness for the characterization of the binding sites in HSA.
References
- 1)The Characterization of Two Specific Drug Binding Sites on Human Serum Albumin
- 2)Further Characterization of Specific Drug Binding Sites on Human Serum Albumin
- 3)Fluorescent Dye Cocktail for Multiplex Drug-Site Mapping on Human Serum Albumin
参考文献
文章/手册
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。
