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CAS RN: 6478-73-5 | 产品编码: D5146
5,6-Dichlorobenzimidazole
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技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 208.0 to 212.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 210 °C |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
| HS编码* | 2933.99-000 |
应用
5,6-Dichlorobenzimidazole: For the Preparation of 5,6-Dichlorobenzimidazole 1-β- D-Ribofuranoside (DRB) [D4292], and etc.
5,6-Dichlorobenzimidazole is a starting compound for the preparation of 5,6-dichlorobenzimidazole 1-β-D-ribofuranoside (DRB) [D4292], which is a powerful inhibitor of casein kinase-2 (CK-2). 5,6-Dichlorobenzimidazole is also used to synthesize antibacterial benzimidazoles, and etc. For your reference, 5,6-dichlorobenzimidazole hydrochloride is [D4295].
References
- Ribofuranosyl-benzimidazole derivatives as inhibitors of casein kinase-2 and casein kinase-1
- Synthesis of Nucleosides (a review)
- Synthesis and antiparasitic activity of 1H-benzimidazole derivatives
- Synthesis and biological evaluations of novel benzimidazoles as potential antibacterial agents
- Synthesis and in vitro antimicrobial activity of some novel substituted benzimidazole derivatives having potent activity against MRSA
参考文献
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