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CAS RN: 462-20-4 | 产品编码: D4586
Dihydrolipoic Acid
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技术规格
| Appearance | Colorless to Light orange to Yellow clear liquid to slightly cloudy liquid |
| Purity(GC) | min. 97.0 % |
| Purity(Neutralization titration) | min. 97.0 % |
| Purity(Iodometric Titration) | min. 97.0 % |
物性（参考值）
| 沸点 | 175 °C/0.08 mmHg |
| 闪点 | 172 °C |
| 比重 | 1.14 |
| 折射率 | 1.52 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | RH0525000 |
运输信息
| HS编码* | 2930.90-900 |
应用
Aihydrolipoic Acid: A Powerful Antioxidant and a Radical Scavenger
α-Lipoic acid [L0058] and its reduced form, dihydrolipoic acid, are powerful antioxidants. Dihydrolipoic acid also scavenges superoxide and peroxyl radicals and can regenerate thioredoxin (a class of small redox proteins), vitamin C [A0537], and glutathione oxidized form [G0073] to its reduced form [G0074], which in turn can recycle vitamin E [T0251]. Dihydrolipoic acid is a racemic compound but the R-enantiomer is thought to be more bioavailable compared to the S-enantiomer.
References
- Neuroprotection by the metabolic antioxidant α-lipoic acid
- The pharmacology of the antioxidant lipoic acid (a review)
- Molecular aspects of lipoic acid in the prevention of diabetes complications (a review)
- Antioxidant and Prooxidant Activities of α-Lipoic Acid and Dihydrolipoic Acid (a review)
- Lipoic acid as a novel treatment for Alzheimer's disease and related dementias (a review)
- Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential (a review)
参考文献
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