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CAS RN: 208255-80-5 | 产品编码: D4257
DAPT
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纯度/分析方法: >97.0%(HPLC)
别名：
- (3,5-二氟苯乙酰基)-Ala-Phg-OtBu
- (3,5-二氟苯乙酰基)-L-丙氨酰基-L-2-苯基甘氨酸叔丁酯
- (S)-2-[(S)-2-[2-(3,5-二氟苯基)乙酰氨基]丙酰氨基]-2-苯基乙酸叔丁酯
- (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu
- (3,5-Difluorophenylacetyl)-L-alanyl-L-2-phenylglycine tert-Butyl Ester
- tert-Butyl (S)-2-[(S)-2-[2-(3,5-Difluorophenyl)acetamido]propanamido]-2-phenylacetate
产品文档：
| 产品编码 | D4257 |
| 纯度/分析方法 | >97.0%(HPLC) |
| 分子式/分子量 | C__2__3H__2__6F__2N__2O__4 = 432.47 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 25MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 208255-80-5 |
| Reaxys-RN | 9588440 |
| PubChem物质ID | 253659655 |
| MDL编号 | MFCD04974585 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Elemental analysis(Nitrogen) | 6.20 to 6.70 % |
| NMR | confirm to structure |
物性（参考值）
GHS
相关法规
运输信息
| HS编码* | 2924.29-000 |
应用
γ-Secretase Inhibitor
References
- 1)Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
- 2)The Notch signaling inhibitor DAPT down-regulates cdk5 activity and modulates the distribution of neuronal cytoskeletal proteins
- 3)Notch signaling: A simple pathway becomes complex
- 4)The Notch response inhibitor DAPT enhances neuronal differentiation in embryonic stem cell-derived embryoid bodies independently of sonic hedgehog signaling
参考文献
TCIMail
[TCIMAIL No.162] γ-Secretase Inhibitor[Featured Products] Regenerative Medicine Related Reagents
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![DAPT [Optimized for Cell Culture]](/medias/Tci-300-D6295.jpg?context=bWFzdGVyfHJvb3R8MTA3ODR8aW1hZ2UvanBlZ3xhR0UxTDJnMFpTODVORFk0TlRRMk56RXhOVGd5TDFSamFTMHpNREJmUkRZeU9UVXVhbkJufDMyNTExODg3MjYzNTFmMjNjYzk3MjBjZjIzOWE1YzAxNWYyYWFlNDExZTZmN2VlZWJiMmFmM2RmYTAxNTBhMDc "DAPT [Optimized for Cell Culture]")