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CAS RN: 512-04-9 | 产品编码: D1474
Diosgenin
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| 产品编码 | D1474 |
| 纯度/分析方法 | >95.0%(GC) |
| 分子式/分子量 | C__2__7H__4__2O__3 = 414.63 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 512-04-9 |
| PubChem物质ID | 87567972 |
| SDBS (AIST Spectral DB) | 11108 |
| Merck Index (14) | 3295 |
| MDL编号 | MFCD00016887 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 205.0 to 208.0 °C |
| Specific rotation [a]20/D | -123 to -127 deg(C=1, CHCL3) |
物性（参考值）
| 熔点 | 205 °C |
| 比旋光度 [α]D | -126° (C=1,CHCl3) |
GHS
相关法规
| RTECS# | WH1450000 |
运输信息
| HS编码* | 2932.99-000 |
应用
Diosgenin: A Steroid Sapogenin with Multiple Biological and Pharmacological Activities
Diosgenin is a naturally occurring steroid sapogenin found abundantly in legumes and yams. Diosgenin is often used a precursor of various synthetic steroidal agents.1) On the other hand, it has been reported that diosgenin has multiple biological and pharmacological activities, including anticancer, cardiovascular protective, anti-diabetes, neuroprotective, immunomodulatory, estrogenic, and skin protective effects.2,3) In addition, recently diosgenin has been demonstrated to improve memory and reduced axonal degeneration in an Alzheimer's disease mouse model.4,5) (The product is for research purpose only.)
References
- 1) Steroid research at Syntex: “the Pill” and cortisone (a review)
- 2) Cancer chemopreventive and therapeutic effects of diosgenin, a food saponin (a review)
- 3) A review on pharmacological and analytical aspects of diosgenin: a concise report (a review)
- 4) Diosgenin is an exogenous activator of 1,25D3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice
- 5) Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D3-MARRS.
参考文献
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技术规格
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