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CAS RN: 2499715-43-2 | 产品编码: C3902
CPO-PFP
×
纯度/分析方法: >98.0%(HPLC)(qNMR)
别名：
- 4-(3-氧代环丙-1-烯-1-基)丁酸五氟苯酯
- 4-(3-氧代-1-环丙烯-1-基)丁酸五氟苯酯
- 3-氧代-1-环丙烯-1-丁酸2,3,4,5,6-五氟苯酯
- Perfluorophenyl 4-(3-Oxocycloprop-1-en-1-yl)butanoate
- Pentafluorophenyl 4-(3-Oxo-1-cyclopropen-1-yl)butanoate
- 3-Oxo-1-cyclopropene-1-butanoic Acid 2,3,4,5,6-Pentafluorophenyl Ester
产品文档：
| 产品编码 | C3902 |
纯度/分析方法 
|
>98.0%(HPLC)(qNMR) |
| 分子式/分子量 | C__1__3H__7F__5O__3 = 306.19 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷冻 (-20°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 光,湿气 (分解),加热 |
| 包装和容器
|
100MG-Glass Bottle with Plastic Insert （查看图片）, 500MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 2499715-43-2 |
| Reaxys-RN | 41868973 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 64.0 to 68.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 66 °C |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
| HS编码* | 2918.30-000 |
应用
A Derivative of Cyclopropenone (CPO) to Precisely Modify the N-Terminal Cysteine Residue
Due to the active ester moiety, CPO-PFP is used as a cyclopropenone (CPO) incorporating reagent to react with primary amines. The cyclopropenone (CPO) moiety can precisely modify the N-terminal cysteine and does not react with non-N-terminal cysteine residues or other nucleophilic side chains. After the N-terminal modification of proteins with CPO, it is possible to introduce two different modifications on a single protein targeting the cysteine residues by treating internal cysteine residues with other cysteine modification reagents.
References
- Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
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