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CAS RN: 17321-77-6 | 产品编码: C3897
Clomipramine Hydrochloride
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| 产品编码 | C3897 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__9H__2__3ClN__2·HCl = 351.32 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,湿气 (吸湿) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 17321-77-6 |
| Reaxys-RN | 4168494 |
| MDL编号 | MFCD00069234 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Precipitation Titration) | min. 98.0 % |
| Melting point | 191.0 to 195.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 193 °C |
| 在水中的溶解度 | 250 g/l 20 °C |
| 溶解性（可溶于） | 乙醇 |
| 溶解性（不溶于） | 二乙醚 |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相关法规
运输信息
| HS编码* | 2933.99-000 |
应用
Clomipramine: A Selective Serotonin Reuptake Inhibitor
Clomipramine hydrochloride is a selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitor and is used as a tricyclic antidepressant in clinical. (The product is for research purpose only.)
Reference
- Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder
- Clinical pharmacokinetics of clomipramine (a review)
- Optimised procedures for the reversed-phase liquid chromatographic analysis of formulations containing tricyclic antidepressants
- Optimization and validation of spectrofluorimetric method for the determination of clomipramine hydrochloride via ion-pair complexation with alizarin red S
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