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CAS RN: 987-78-0 | 产品编码: C3438
Cytidine 5'-Diphosphocholine
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技术规格
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 209.0 to 213.0 °C |
| Specific rotation [a]20/D | +17.0 to +21.0 deg(C=1, H2O) |
| Solubility in Water | almost transparency |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 211 °C |
| 水溶性 | 可溶 |
GHS
相关法规
| RTECS# | GA4027000 |
运输信息
| HS编码* | 2934.99-000 |
应用
Citicoline: An Essential Intermediate in the Major Pathway for the Biosynthesis of the Structural Phospholipids
Citicoline (CDP-choline), a naturally occurring endogenous nucleoside, is an essential intermediate in the major pathway for the biosynthesis of the structural phospholipids of cell membranes, including neurons. It has been reported that citicoline activates the biosynthesis of structural phospholipids in the neuronal membrane, increases cerebral metabolism and increases the level of various neurotransmitters, including acetylcholine and dopamine. Therefore, citicoline is used for the treatment of CNS disorders, in clinical. (The product is for research purpose only.)
References
- Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline (a review)
- Citicoline: neuroprotective mechanisms in cerebral ischemia (a review)
- Cytidine 5'-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
- Neuroprotective Properties of Citicoline: Facts, Doubts and Unresolved Issues (a review)
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