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CAS RN: 91832-40-5 | 产品编码: C3111
Cefdinir
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This product has not been tested for potency and is guaranteed for chemical purity.
| 产品编码 | C3111 |
纯度/分析方法 
|
>97.0%(T)(HPLC) |
| 分子式/分子量 | C__1__4H__1__3N__5O__5S__2 = 395.41 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 91832-40-5 |
| Reaxys-RN | 6829362 |
| PubChem物质ID | 253660757 |
| Merck Index (14) | 1920 |
| MDL编号 | MFCD00865030 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Specific rotation [a]20/D | -58.0 to -66.0 deg(C=1,0.1mol/L buffer sol. pH7.0 Phosphate) |
物性（参考值）
| 熔点 | 190 °C(dec.) |
| 比旋光度 [α]D | -65° (C=1,0.1mol/L pH7.0 phoshate Buffer) |
| 最大吸收波长 | 295 nm (DMSO) |
| 水溶性 | 不溶 |
| 溶解性（不溶于） | 乙醇, 乙醚 |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
| RTECS# | XI0367250 |
运输信息
| HS编码* | 2941.90-000 |
应用
Cefdinir: A Third-Generation Cephalosporin More Active Against Gram-Positive Organisms
Cefdinir (FK482) is an oral third-generation cephalosporin with vinyl group at the 3-potition and 2-aminothiazolylhydroxyimino group at the 7-potition of 7-ACA [A1266]. Cefdinir has a broad spectrum of activity against many Gram-negative and Gram-positive organisms, but does not have activity against Pseudomonas aeruginosa. Cefdinir is more active than other cephalosporins (e.g. cephalexin [C2248]) against Gram-positive organisms such as Staphylococcus aureus and strains of the Streptococcus group. Cefdinir is stable to hydrolysis by β-lactamases. (The product is for research purpose only.)
References
- In vitro antibacterial activity of FK482, a new orally active cephalosporin
- Cefdinir: an advanced-generation, broad-spectrum oral cephalosporin (a review)
- Cefdinir: a review of its use in the management of mild-to-moderate bacterial infections (a review)
- Method development for the determination of cefdinir and its related substances by high-performance liquid chromatography
- Polymorphisms and Patent, Market, and Legal Battles: Cefdinir Case Study
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