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CAS RN: 75975-70-1 | 产品编码: C2988
Cephradine Monohydrate
![Cephradine Monohydrate No-Image](/medias/C2988.jpg?context=bWFzdGVyfHJvb3R8NTA4NzZ8aW1hZ2UvanBlZ3xhREl4TDJnMFlTODRPVEl3Tnpjek5qZzVNemMwTDBNeU9UZzRMbXB3Wnd8ZTRmY2Q4YTc4ZGIwZThkZmYyYjdhMjJmZWVhNThjODhmZTY2MDNhMmU0YWUxM2FlODlhZTZkMjUwMGNjZmJiNA)
补充产品信息:
This product has not been tested for potency and is guaranteed for chemical purity.
技术规格
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 96.0 area% |
Purity(Nonaqueous Titration) | min. 96.0 %(calcd.on anh.substance) |
Specific rotation [a]20/D | +85.0 to +89.0 deg(C=0.5, H2O)(calcd.on anh.substance) |
Water | 3.0 to 7.0 % |
物性(参考值)
熔点 | 186 °C(dec.) |
比旋光度 [α]D | 87° (C=0.5,H2O) |
最大吸收波长 | 260(H2O) nm |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
RTECS# | XID336000 |
运输信息
HS编码* | 2941.90-000 |
应用
Cephradine: A First-Generation Semisynthetic Cephalosporin Antibiotic
Cephradine is a first-generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminodesacetoxycephalosporanic acid (7-ADCA) [A2075]. Cephradine has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, and similar antibiotic activity with cephalexin [C2248].
References
- Cephradine (a review)
- Determination of ampicillin, amoxicillin, cephalexin, and cephradine in plasma by high-performance liquid chromatography using fluorometric detection
- Determination of cephalosporins utilizing thin-layer chromatography with fluorescamine detection
- Validation of a capillary electrophoresis method for the determination of cephradine and its related impurities
- Determination of the cephalosporin antibiotic cephradine in human plasma by high-performance liquid chromatography with ultraviolet detection
- Rapid and simple method for determination of cephradine in human plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS): Application to the bioequivalence study
参考文献
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