Maximum quantity allowed is 999
请选择数量
CAS RN: 5638-76-6 | 产品编码: B6621
Betahistine
×
![]()
×
| 产品编码 | B6621 |
| 纯度/分析方法 | >98.0%(GC)(T) |
| 分子式/分子量 | C__8H__1__2N__2 = 136.20 |
| 外观与形状（20°C） | 液体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气 |
| CAS RN | 5638-76-6 |
| Reaxys-RN | 112294 |
| MDL编号 | MFCD00006362 |
技术规格
| Appearance | Colorless to Yellow to Orange clear liquid |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
| 沸点 | 114 °C/30 mmHg |
| 闪点 | 96 °C |
| 比重 | 0.99 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | UT5552000 |
运输信息
| HS编码* | 2933.39-000 |
应用
Betahistine: A Histamine H1 Receptor Agonist/H3 Antagonist
Betahistine and its methanesulfonate [B1424] are structural analogs of histamine [H0146, dihydrochloride] that act as both partial histamine H1-receptor agonists and histamine H3 receptor antagonists in neuronal tissue. Betahistine increases histamine turnover and release by blocking presynaptic H3-receptors and inducing H3-receptor downregulation.1-3) Betahistine has been reported to increase vestibular blood flow and is used clinically as an antivertigo agent.2,3) Recently, it has been reported that betahistine induced the recall of forgotten memories in mice.4) (The product is for research use only.)
References
- 1) Actions of betahistine at histamine receptors in the brain
- 2) Betahistine increases vestibular blood flow
- 3) Histamine and betahistine in the treatment of vertigo: Elucidation of mechanisms of action (a review)
- 4) Central Histamine Boosts Perirhinal Cortex Activity and Restores Forgotten Object Memories
- 5) LC-MS-MS analysis of 2-pyridylacetic acid, a major metabolite of betahistine: application to a pharmacokinetic study in healthy volunteers
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。