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CAS RN: 36330-85-5 | 产品编码: B2491
Fenbufen
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| 规格 | 单价 | 同一天 | 2-3个工作日 | 数量 |
|---|---|---|---|---|
| 5G |
S$69.00
|
21 | 4 |
|
| 产品编码 | B2491 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__6H__1__4O__3 = 254.29 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| CAS RN | 36330-85-5 |
| Reaxys-RN | 2378560 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 185.0 to 189.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 187 °C |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2918.30-000 |
应用
Fenbufen: A Non-Steroidal and Non-Selective Cyclooxygenase (COX) Inhibitor
Fenbufen is a non-steroidal and non-selective cyclooxygenase (COX) inhibitor with anti-inflammatory properties. Fenbufen is a prodrug and its major metabolite, 4-biphenylacetic acid [B1278], is a potent inhibitor of prostaglandin synthesis. The mechanism of action is mainly through inhibition of the enzyme COX in the arachidonic acid pathway, resulting in reduced prostaglandin synthesis. (The product is for research purpose only.)
Reference
- Pharmacologic properties of fenbufen
- Fenbufen: a review of its pharmacological properties and therapeutic use in rheumatic diseases and acute pain
- A review of selected investigational nonsteroidal antiinflammatory drugs of the 1980s
- Microextraction by packed sorbent and high performance liquid chromatography determination of seven non-steroidal anti-inflammatory drugs in human plasma and urine
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