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CAS RN: 65710-07-8 | 产品编码: A3395
Apramycin Sulfate
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纯度/分析方法: >95.0%(HPLC)
别名：
- 硫酸阿布拉霉素
- 暗霉素II
- O-4-氨基-4-脱氧-α-D-吡喃葡萄糖基-(1→8)-O-(8R)-2-氨基-2,3,7-三脱氧基-7-(甲基氨基)-D-甘油-α-D-allo-辛二醛糖基-1,5:8,4-二吡喃糖基-(1→4)-2-脱氧-D-链霉胺硫酸盐
- Nebramycin II
- O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-Streptamine Sulfate
产品文档：
技术规格
| Appearance | Light yellow to Yellow powder to crystal |
| Purity(HPLC)(CAD) | min. 95.0 area% |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 168 °C |
GHS
相关法规
运输信息
| HS编码* | 2941.90-000 |
应用
Apramycin Sulfate: A Broad-Spectrum Aminoglycoside Antibiotic against Multidrug-Resistant Gram-Negative Bacteria
Apramycin sulfate is a broad-spectrum aminoglycoside antibiotic first isolated from Streptomyces tenebrarius.1) As an aminoglycoside antibiotic apramycin binds to the bacterial ribosomal site and interferes with the bacterial protein synthesis. The overall spectrum includes many aerobic or facultative anaerobic Gram-negative bacteria, including multidrug-resistant Enterobacteriaceae and Acinetobacter baumannii.2,3) Apramycin sulfate is mainly used as a veterinary medicine.4) (The product is for research purpose only.)
References
- 1) Apramycin, a unique aminocyclitol antibiotic
- 2) In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii
- 3) In vitro Apramycin Activity against multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa
- 4) Apramycin (a review)
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