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CAS RN: 129722-12-9 | 产品编码: A2496
Aripiprazole
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技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
物性（参考值）
| 熔点 | 149 °C |
| 水溶性 | 不溶 |
| 在水中的溶解度 | 0.045 mg/l 25 °C |
| 溶解性（不溶于） | 甲醇 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | VC8275950 |
运输信息
| HS编码* | 2933.59-000 |
应用
Aripiprazole: A Partial Agonist at Dopamine D2 and Serotonin 5-HT1A Receptors
Aripiprazole is a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, and is an antagonist at 5-HT2A receptors. Aripiprazole is a third-generation antipsychotic agent indicated for use in the treatment of schizophrenia. Although the exact mechanism is unknown, the partial agonism and antagonism are believed to be the functional basis of its therapeutic efficacy. (The product is for research purpose only.)
References
- Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors
- Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology
- The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor
- Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes
- Aripiprazole: a comprehensive review of its pharmacology, clinical efficacy, and tolerability (a review)
- Aripiprazole (a review on the analytical methods)
参考文献
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