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CAS RN: 123524-52-7 | 产品编码: A2433
Azelnidipine
![Azelnidipine No-Image](/medias/A2433.jpg?context=bWFzdGVyfHJvb3R8NTA0NDh8aW1hZ2UvanBlZ3xhR00zTDJnek9DODRPVEU1TmpZek9ETTNNakUwTDBFeU5ETXpMbXB3Wnd8Yzc1YTNlOTBjMzc0MzVlYmZlN2RkZmU1OTIzMjQxN2E4YzQwZWNmNTQ5ODJhMjdjNzk5NTUzNjA3ZWM5ZWQ3Mg)
纯度/分析方法: >98.0%(T)(HPLC)
别名:
- 阿折地平
- 2-氨基-1,4-二氢-6-甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸3-[1-(二苯基甲基)-3-氮杂啶] 5-异丙酯
- 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl Ester
- 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
产品文档:
产品编码 | A2433 |
纯度/分析方法 | >98.0%(T)(HPLC) |
分子式/分子量 | C__3__3H__3__4N__4O__6 = 582.66 |
外观与形状(20°C) | 固体 |
储存温度 | 室温 (15°C以下阴凉干燥处) |
储存在惰性气体下 | 存放于惰性气体之中 |
应避免的情况 | 空气 |
包装和容器 | 1G-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 123524-52-7 |
Reaxys-RN | 7420123 |
PubChem物质ID | 253661997 |
Merck Index (14) | 907 |
MDL编号 | MFCD00865803 |
技术规格
Appearance | Light orange to Yellow to Green powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
物性(参考值)
水溶性 | 不溶 |
溶解性(可溶于) | 甲醇, 乙醇 |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
RTECS# | US7968332 |
运输信息
HS编码* | 2933.99-000 |
应用
Azelnidipine: An L-type Calcium Channels Selective Calcium Channel Antagonist
Azelnidipine, also known as CS-905, is a long-acting dihydropyridine calcium channel antagonist with selectivity for L-type calcium channels for the treatment of hypertension. (The product is for research purpose only.)
References
- Azelnidipine (a review)
- Azelnidipine, a long-acting calcium channel blocker with slow onset and high vascular affinity (a review)
- H. Koike, T. Kimura, T. Kawasaki, T. Sada, T. Ikeda, A. Sanbuissho, H. Saito, Annu. Rep. Sankyo Res. Lab. 2003, 54, 1.
- Azelnidipine and amlodipine [A2353]: a comparison of their pharmacokinetics and effects on ambulatory blood pressure
- Calcium channel blocker azelnidipine enhances vascular protective effects of AT1 receptor blocker olmesartan
- Azelnidipine, a newly developed long-acting calcium antagonist, inhibits tumor necrosis factor-α-induced interleukin-8 expression in endothelial cells through its anti-oxidative properties
- Spectroscopic studies on the interaction of azelnidipine with bovine serum albumin
参考文献
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