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CAS RN: 76855-69-1 | 产品编码: A1124
(3R,4R)-4-Acetoxy-3-[(R)-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone
![(3R,4R)-4-Acetoxy-3-[(R)-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone No-Image](/medias/A1124.jpg?context=bWFzdGVyfHJvb3R8NDk0OTh8aW1hZ2UvanBlZ3xhREptTDJnek9DODRPVEU1TlRZMk1qVTBNVEV3TDBFeE1USTBMbXB3Wnd8NTQ3M2RjMWM1ZGZhNjZmMWE4OWMwMWVhNDVkZTc5MjM0NDkyODJjYTc3ZDk1MmUzOTkwYjU4M2Q1NjcyM2I4Ng)
技术规格
Appearance | White to Almost white powder to crystal |
Purity(with Total Nitrogen) | min. 98.0 % |
Melting point | 107.0 to 110.0 °C |
Specific rotation [a]20/D | +53.0 to +59.0 deg(C=0.5, Toluene) |
Solubility in Methanol | almost transparency |
NMR | confirm to structure |
物性(参考值)
熔点 | 108 °C |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. H411 : Toxic to aquatic life with long lasting effects. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
运输信息
UN编号 | UN3077 |
类别 | 9 |
包装类别 | III |
HS编码* | 2933.79-000 |
应用
Riluzole: A Neuroprotective Agent
References
- Y. Nagao, T. Kumagai, S. Tamai, T. Abe, Y. Kuramoto, T. Taga, S. Aoyagi, Y. Nagase, M. Ochiai, Y. Inoue, E. Fujita, J. Am. Chem. Soc. 1986, 108, 4673.
- L. M. Fuentes, I. Shinkai, T. N. Salzmann, ibid. 1986, 108, 4675.
- F. Shirai, T. Nakai, J. Org. Chem. 1987, 52, 5491.
- T. Shibata, K. Iino, T. Tanaka, T. Hashimoto, Y. Kameyama, Y. Sugimura, Tetrahedron Lett. 1985, 26, 4739.
- M. Sugimura, T. Hiraoka, YAKUGAKU ZASSHI 1987, 107, 175.
参考文献