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CAS RN: 19171-19-8 | Product Number: P2074
Pomalidomide
Purity: >98.0%(HPLC)
Synonyms:
- 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Quantity |
---|---|---|---|---|
25MG |
S$246.00
|
22 | ≥40 |
|
100MG |
S$736.50
|
≥60 | ≥40 |
|
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* The storage conditions are subject to change without notice.
Product Number | P2074 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__1__3H__1__1N__3O__4 = 273.25 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 25MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 19171-19-8 |
Reaxys Registry Number | 8340987 |
PubChem Substance ID | 253660183 |
Merck Index (14) | 135 |
MDL Number | MFCD12756407 |
Specifications
Appearance | White to Yellow to Green powder to crystaline |
Purity(HPLC) | min. 98.0 area% |
Properties (reference)
Melting Point | 313 °C(dec.) |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
RTECS# | NR3397905 |
Transport Information:
H.S.code* | 2925.19-000 |
Application
A Potent Anti-Myeloma, Anti-Inflammatory and Immunomodulatory Agent, Pomalicomide
Pomalidomide (CC-4047), a thalidomide analog, is an immunomodulatory agent with numerous effects on the body's immune system, and has potent anti-myeloma and anti-inflammatory activities in vitro and in vivo. Pomalidomide inhibits the cytokines tumor necrosis factor-α (TNF-α), interleukins (IL) 1β, 6, 12, and granulocyte macrophage-colony stimulating factor (GM-CSF).
References
- Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity
- Lenalidomide and CC-4047 Inhibit the Proliferation of Malignant B Cells while Expanding Normal CD34+ Progenitor Cells
- The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
- Pharmacological properties of thalidomide and its analogues
- Pomalidomide therapy for myeloma
- Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma
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Articles/Brochures
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