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CAS RN: 83-43-2 | Product Number: M1665
6α-Methylprednisolone
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Purity: >98.0%(HPLC)
Synonyms:
- 11β,17α,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione
- Medrol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Quantity |
|---|---|---|---|---|
| 1G |
S$130.50
|
4 | ≥40 |
|
| 5G |
S$370.50
|
28 | 11 |
|
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* The storage conditions are subject to change without notice.
| Product Number | M1665 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__3__0O__5 = 374.48 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 83-43-2 |
| Reaxys Registry Number | 2340300 |
| PubChem Substance ID | 87560014 |
| Merck Index (14) | 6111 |
| MDL Number | MFCD00010591 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +79.0 to +86.0 deg(C=1, Dioxane) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 237 °C |
| Specific Rotation | 82° (C=1,Dioxane) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | TU4146000 |
Transport Information:
| H.S.code* | 2937.29-000 |
Application
Methylprednisolone (medrol): A Glucocorticosteroid with Potent Anti-Inflammatory Activities
6α-Methylprednisolone (medrol) is a classified as a glucocorticosteroid which cause profound and varied metabolic effects. In addition, they affect immune system. It is reported that medrol has a more potent anti-inflammatory effect than cortisone [C1317] and hydrocortisone [H0533]. Furthermore, medrol has far less effects of electrolyte as a glucocorticosteroid. (The product is for research purpose only.)
References
- The neuroprotective pharmacology of methylprednisolone (a review)
- The mechanism of action of methylprednisolone in the treatment of multiple sclerosis (a review)
- Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids
- Identification of ten corticosteroids in human hair by liquid chromatography-ionspray mass spectrometry
- Liquid chromatographic-mass spectrometric analysis of 11 glucocorticoid residues and an optimization of enzymatic hydrolysis conditions in bovine liver
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