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CAS RN: 104054-27-5 | Product Number: A3259
Atipamezole
![Atipamezole No-Image](/medias/A3259.jpg?context=bWFzdGVyfHJvb3R8MzczMjR8aW1hZ2UvanBlZ3xhR1ppTDJoak5DODVNRGc1T0RnM016TTROVEkyTDBFek1qVTVMbXB3Wnd8OWQ3MDg1YjU1N2NhNDA1ZTI0ZWNhZmJlOGEzMzk4NzhmOGVhZGEyZmNlZjc2ODMyNjg2ZWEwOWNiNTVjNDZkYg)
Purity: >98.0%(GC)
Synonyms:
- 4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
Product Documents:
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Product Number | A3259 |
Purity / Analysis Method | >98.0%(GC) |
Molecular Formula / Molecular Weight | C__1__4H__1__6N__2 = 212.30 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 104054-27-5 |
Reaxys Registry Number | 8142269 |
PubChem Substance ID | 468590199 |
Merck Index (14) | 861 |
MDL Number | MFCD00864502 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(GC) | min. 98.0 % |
Melting point | 127.0 to 131.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 129 °C |
GHS
Related Laws:
RTECS# | NI6138500 |
Transport Information:
H.S.code* | 2933.29-000 |
Application
Atipamezole: A Selective Antagonist of Both Centrally and Peripherally Located α2-Adrenoceptor
Atipamezole is a selective antagonist of both centrally and peripherally located α2-adrenoceptor indicated for the reversal of the sedative and analgesic effects of α2-adrenoceptor agonists, such as dexmedetomidine [D5062] and medetomidine [M3314], in animals. (The product is for research purpose only.)
References
- Pharmacological profiles of medetomidine and its antagonist, atipamezole (a review)
- The α2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects
- Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective α2-adrenoceptor antagonist (a review)
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