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CAS RN: 64506-49-6 | Product Number: M3730
Sofalcone
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-[5-[(3-Methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]acetic Acid
- 2-[5-[(3-Methylbut-2-en-1-yl)oxy]-2-[3-[4-[(3-methylbut-2-en-1-yl)oxy]phenyl]acryloyl]phenoxy]acetic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 5G |
$72.00
|
36 | Contact Us |
| 25G |
$250.00
|
28 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | M3730 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__3__0O__6 = 450.53 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 64506-49-6 |
| Reaxys Registry Number | 2191482 |
| MDL Number | MFCD00868207 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 141.0 to 145.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 143 °C |
GHS
Related Laws:
| RTECS# | AI8987000 |
Transport Information:
| H.S.code* | 2918.99-000 |
Application
Sofalcone: A Gastric Antiulcer Agent
Sofalcone is a stable synthetic analog of sophoradin, which is found in Sophora tonkinensis, an herb used in traditional Chinese medicine. Sofalcone has been used as a gastric antiulcer agent, and is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium. (The product is for research use only.)
References
- Sofalcone, an anti-ulcer chalcone derivative, suppresses inflammatory crosstalk between macrophages and adipocytes and adipocyte differentiation: Implication of heme-oxygenase-1 induction
- Sofalcone, a gastric mucosa protective agent, increases vascular endothelial growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells
Product Documents (Note: Some products will not have analytical charts available.)
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