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CAS RN: 3505-38-2 | Product Number: C3057
Carbinoxamine Maleate
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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| Product Number | C3057 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__9ClN__2O·C__4H__4O__4 = 406.86 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 3505-38-2 |
| Related CAS RN | 486-16-8 |
| Reaxys Registry Number | 6557352 |
| PubChem Substance ID | 253662526 |
| Merck Index (14) | 1799 |
| MDL Number | MFCD00082461 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(excluding counter anion) |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 116.0 to 121.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 119 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | US6350000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2933.39-000 |
Application
Carbinoxamine maleate: A Histamine H1-Receptor Antagonist.
Carbinoxamine maleate, a first generation antihistamine, is a histamine H1-receptor antagonist. Carbinoxamine competes with histamine (type H1) for receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract.
References
- Comparison of the effects of eleven histamine H1-receptor antagonists on monoamine turnover in the mouse brain
- Screening procedure for the detection of alkanolamine antihistamines and their metabolites in urine using computerized gas chromatography-mass spectrometry
- Determination of pseudoephedrine hydrochloride and carbinoxamine maleate in combination drug formulation by liquid chromatography
- A. M. Mansour, J. AOAC Int. 1998, 81, 958.
- Quantitative chiral analysis of carbinoxamine, doxylamine, and orphenadrine by capillary zone electrophoresis
- Determination of carbinoxamine maleate in pharmaceuticals by direct and differential pulse polarography
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