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CAS RN: 5508-58-7 | Product Number: A2459
Andrographolide
![Andrographolide No-Image](/medias/A2459.jpg?context=bWFzdGVyfHJvb3R8NjM1ODd8aW1hZ2UvanBlZ3xhR001TDJnNE5pODRPVEU1TmpZMU1qYzVNREEyTDBFeU5EVTVMbXB3Wnd8NWY2Yzc1NWRhOWI4MjA3Mzg3ODhkMGZmZTYwYTgwNDg1NDBhYTkzMjdlMjc1YjMxNDU0OGQ4NzhjMDdhZWVkMQ)
Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
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5G |
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Product Number | A2459 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__0H__3__0O__5 = 350.46 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 5508-58-7 |
Reaxys Registry Number | 5609598 |
PubChem Substance ID | 253659551 |
Merck Index (14) | 633 |
MDL Number | MFCD07778082 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Specific rotation [a]20/D | -124 to -129 deg(C=1.5, AcOH) |
Properties (reference)
Melting Point | 231 °C |
Specific Rotation | -126° (C=1.5,AcOH) |
Maximum Absorption Wavelength | 223(MeOH) nm |
GHS
Related Laws:
RTECS# | LU3490750 |
Transport Information:
H.S.code* | 2932.20-000 |
Application
Studies on the Pharmacological Activity of Andrographolide as a NF-κB Activation Inhibitor and an Anti-inflammatory Agent
References
- Immunostimulant agents from Andrographis paniculata
- Andrographolide Attenuates Inflammation by Inhibition of NF-κB Activation through Covalent Modification of Reduced Cysteine 62 of p50
- Y.-F. Xia, B.-Q. Ye, Y.-D. Li, J.-G. Wang, X.-J. He, X. Lin, X. Yao, D. Ma, A. Slungaard, R. P. Hebbel, N. S. Key, J.-G. Geng, J. Immunol. 2004, 173, 4207.
- Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti- inflammatory effect
- In vitro and in vivo anti-inflammatory effects of andrographolide
- Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata
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