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CAS RN: 35941-71-0 | Product Number: T3176
Tiaramide Hydrochloride
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Purity: >98.0%(T)
Synonyms:
- 5-Chloro-3-[[4-(2-hydroxyethyl)piperazin-1-yl]carbonylmethyl]-2-benzothiazolinone Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
$112.00
|
2 | 8 | Contact Us | |
| 100MG |
$339.00
|
3 | 10 | Contact Us |
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* The storage conditions are subject to change without notice.
| Product Number | T3176 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__5H__1__8ClN__3O__3S·HCl = 392.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 35941-71-0 |
| Related CAS RN | 32527-55-2 |
| Reaxys Registry Number | 6081227 |
| PubChem Substance ID | 253660473 |
| Merck Index (14) | 9424 |
| MDL Number | MFCD01702832 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 160 °C |
GHS
| Signal Word | Warning |
| Hazard Statements | H320 : Causes eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
Related Laws:
| RTECS# | TL7050000 |
Transport Information:
| H.S.code* | 2934.20-000 |
Application
Tiaramide Hydrochloride: A Non-Acidic and Non-Steroidal Anti-Inflammatory Agent with No Inhibiting Action of COX
Tiaramide hydrochloride, a benzothiazolinone derivative, is a non-acidic and non-steroidal antiinflammatory drug (NSAID). It has almost the same antiinflammatory activity and analgesic effect as benzydamine hydrochloride [B3751], but does not inhibit cyclooxygenase (COX). (The product is for research purpose only.)
References
- Antiinflammatory activity of tiaramide hydrochloride, 4-[(5-chloro-2-oxo-3-benzothiazolinyl)acetyl]-1-piperazineethanol hydrochloride
- K. Tsurumi, Y. Hiramatsu, M. Nozaki, M. Hayashi, H. Fujimura, Arzneim.-Forsch. 1972, 22, 716.
- Pharmacological actions of tiaramide hydrochloride, a new antiinflammatory drug
- K. Tsurumi, Y. Hiramatsu, M. Nozaki, M. Hayashi, H. Fujimura, Arzneim.-Forsch. 1972, 22, 724.
- Central and peripheral analgesic action of nonacidic nonsteroidal anti-inflammatory drugs in mice and rats
- H. Nakamura, A. Shimoda, K. Ishii, T. Kadokawa, Arch. Int. Pharmacodyn. Ther. 1986, 282, 16.
- Preparation and evaluation of beads made of different calcium alginate compositions for oral sustained release of tiaramide
- High performance liquid chromatographic determination of epirizole and tiaramide in pharmaceutical preparations
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