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CAS RN: 77086-22-7 | Product Number: M3393
(+)-MK 801 Maleate
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Purity: >98.0%(HPLC)
Synonyms:
- (5S,10R)-5-Methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene Maleate
- Dizocilpine Maleate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 25MG |
$164.00
|
11 | 16 |
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* The storage conditions are subject to change without notice.
| Product Number | M3393 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__5N·C__4H__4O__4 = 337.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 77086-22-7 |
| Reaxys Registry Number | 7158220 |
| PubChem Substance ID | 468592439 |
| MDL Number | MFCD00082465 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation | +115 to +121 deg(C=0.6, ｴﾀﾉｰﾙ) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 210 °C |
GHS
Related Laws:
| RTECS# | HP1093575 |
Transport Information:
| H.S.code* | 2933.49-000 |
Application
(+)-MK 801 maleate: A Potent, Selective and Non-Competitive N-methyl-D-aspartate (NMDA) receptor antagonist
(+)-MK 801 maleate (its other name: dizocilpine maleate) is a potent, selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, and has been reported to display various physiological effects, mainly involving the central nervous system.1-3) Therefore, (+)-MK 801 maleate has been used as an important tool for the screening of antipsychotic potential of new compounds.4) (The product is for research purpose only.)
References
- 1) The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist
- 2) Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801
- 3) Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity (a review)
- 4) Consequences of early life MK-801 administration: Long-term behavioural effects and relevance to schizophrenia research (a review)
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