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CAS RN: 147591-46-6 | Product Number: I1108
ID 8
×
Purity: >98.0%(GC)
Synonyms:
- 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
$96.00
|
4 | 9 | It can be shipped in about 2 weeks after ordering | |
| 50MG |
$329.00
|
10 | 10 | It can be shipped in about 2 weeks after ordering |
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| Product Number | I1108 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__4N__2O__4 = 298.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 147591-46-6 |
| Reaxys Registry Number | 5825601 |
| PubChem Substance ID | 468592099 |
| MDL Number | MFCD00593367 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 266 °C(dec.) |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) Inhibitor
ID 8 (1) was reported as an indole derivative that can sustain embryonic stem cell self-renewal in long-term culture.1)1 inhibits dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2) 1 supports Wnt-induced human embryonic stem cell proliferation and survival without fibroblast growth factor (FGF) and tumor growth factor-β (TGF-β) supplementation.2)
References
- 1) Indole derivatives sustain embryonic stem cell self-renewal in long-term culture
- 2) Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion
Documents
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[TCIMAIL No.188] Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) InhibitorProduct Documents (Note: Some products will not have analytical charts available.)
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