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CAS RN: 236395-14-5 | Product Number: E1046
Eslicarbazepine Acetate
Purity: >98.0%(HPLC)(N)
Synonyms:
- BIA 2-093
- (S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
200MG |
$111.00
|
1 | Contact Us |
1G |
$354.00
|
11 | Contact Us |
* Please contact our distributors or
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
Product Number | E1046 |
Purity / Analysis Method | >98.0%(HPLC)(N) |
Molecular Formula / Molecular Weight | C__1__7H__1__6N__2O__3 = 296.33 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 236395-14-5 |
Reaxys Registry Number | 8336447 |
PubChem Substance ID | 253662249 |
MDL Number | MFCD06798333 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(with Total Nitrogen) | min. 98.0 % |
Melting point | 185.0 to 189.0 °C |
Specific rotation [a]20/D | -20.0 to -24.0 deg(C=1, Pyridine) |
Properties (reference)
Melting Point | 187 °C |
Specific Rotation | -22° (C=1,Pyridine) |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H336 : May cause drowsiness or dizziness. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P271 : Use only outdoors or in a well-ventilated area. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
Transport Information:
H.S.code* | 2933.99-000 |
Application
Romifidine: a potent and selective α2-adrenoceptor agonist
Eslicarbazepine acetate (BIA 2-093 or ESL) is a central nervous system (CNS)-active compound with anticonvulsant activity. BIA 2-093 has voltage-gated sodium channel (VGSC) blocking property. BIA 2-093 is metabolized to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine [O0363], which is responsible for pharmacological activity. BIA 2-093 is used as a third generation antiepileptic drugs (AEDs), and is often used in combination with the other AEDs. (The product is for research purpose only.)
References
- Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives
- Metabolism of two new antiepileptic drugs and their principal metabolites S(+)- and R(-)-10,11-dihydro-10-hydroxy carbamazepine
- Enantioselective HPLC-UV method for determination of eslicarbazepine acetate (BIA 2-093) and its metabolites in human plasma
- Eslicarbazepine acetate (BIA 2-093) (a review)
- Drug interactions involving the new second- and third-generation antiepileptic drugs (a review)
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