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CAS RN: 6199-67-3 | Product Number: C3442
Cucurbitacin B
Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
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Product Number | C3442 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__3__2H__4__6O__8 = 558.71 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image), 5MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 6199-67-3 |
Reaxys Registry Number | 2068869 |
PubChem Substance ID | 354335232 |
Merck Index (14) | 2614 |
MDL Number | MFCD07778083 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Water | max. 5.0 % |
Properties (reference)
Melting Point | 179 °C |
Maximum Absorption Wavelength | 290(EtOH) nm |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H300 : Fatal if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | RC6190000 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | II |
H.S.code* | 2915.39-000 |
Application
Cucurbitacin B: A Triterpenoid Reported as a Promising Antitumor Agent
Cucurbitacin B is a triterpenoid compound isolated from Cucurbitaceae and various plants used as folk medicine in Asian countries, and has recently emerged as a potent antitumor agent. Cucurbitacin B is reported to have anti-proliferation effects on a variety of tumors, and the mechanism of action is still controversial. (The product is for research purpose only.)
References
- Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme
- Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells
- Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration
- Triterpenoids for cancer prevention and treatment: current status and future prospects (a review)
- A review on the medicinally important plants of the family Cucurbitaceae (a review)
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