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CAS RN: 123524-52-7 | Product Number: A2433
Azelnidipine
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl Ester
- 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$76.00
|
35 | 0 | It can be shipped in about 2 weeks after ordering | |
| 5G |
$243.00
|
1 | 2 | It can be shipped in about 2 weeks after ordering |
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* The storage conditions are subject to change without notice.
| Product Number | A2433 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__3__3H__3__4N__4O__6 = 582.66 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 123524-52-7 |
| Reaxys Registry Number | 7420123 |
| PubChem Substance ID | 253661997 |
| Merck Index (14) | 907 |
| MDL Number | MFCD00865803 |
Specifications
| Appearance | Light orange to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Solubility in water | Insoluble |
| Solubility (soluble in) | Methanol, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | US7968332 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Azelnidipine: An L-type Calcium Channels Selective Calcium Channel Antagonist
Azelnidipine, also known as CS-905, is a long-acting dihydropyridine calcium channel antagonist with selectivity for L-type calcium channels for the treatment of hypertension. (The product is for research purpose only.)
References
- Azelnidipine (a review)
- Azelnidipine, a long-acting calcium channel blocker with slow onset and high vascular affinity (a review)
- H. Koike, T. Kimura, T. Kawasaki, T. Sada, T. Ikeda, A. Sanbuissho, H. Saito, Annu. Rep. Sankyo Res. Lab. 2003, 54, 1.
- Azelnidipine and amlodipine [A2353]: a comparison of their pharmacokinetics and effects on ambulatory blood pressure
- Calcium channel blocker azelnidipine enhances vascular protective effects of AT1 receptor blocker olmesartan
- Azelnidipine, a newly developed long-acting calcium antagonist, inhibits tumor necrosis factor-α-induced interleukin-8 expression in endothelial cells through its anti-oxidative properties
- Spectroscopic studies on the interaction of azelnidipine with bovine serum albumin
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