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CAS RN: 26471-62-5 | Product Number: T0264
Tolylene Diisocyanate (2,4- ca. 80%, 2,6- ca. 20%)
Purity: >98.0%(GC)
Synonyms:
- Toluene Diisocyanate (2,4- ca. 80%, 2,6- ca. 20%)
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
25G |
$27.00
|
17 | ≥80 |
500G |
$59.00
|
18 | ≥100 |
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* The storage conditions are subject to change without notice.
Product Number | T0264 |
Purity / Analysis Method | >98.0%(GC) |
Molecular Formula / Molecular Weight | C__9H__6N__2O__2 = 174.16 |
Physical State (20 deg.C) | Liquid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
CAS RN | 26471-62-5 |
Reaxys Registry Number | 8188352 |
PubChem Substance ID | 87576244 |
MDL Number | MFCD01778251 |
Specifications
Appearance | Colorless to Light yellow clear liquid |
Purity(GC) | min. 98.0 %(total of isomer) |
Properties (reference)
Melting Point | 14 °C |
Boiling Point | 251 °C |
Flash point | 137 °C |
Specific Gravity (20/20) | 1.22 |
Refractive Index | 1.57 |
Solubility (miscible with) | Ether, Benzene, Acetone |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H330 : Fatal if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. H351 : Suspected of causing cancer. H412 : Harmful to aquatic life with long lasting effects. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
RTECS# | NQ9490000 |
Transport Information:
UN Number | UN2078 |
Class | 6.1 |
Packing Group | II |
H.S.code* | 2929.10-100 |
Application
Reagent for airway hyperresponsiveness (asthma) model
References
- The development of an animal model for TDI asthma
- M. H. Karol, Bull. Eur. Physiopathol. Respir. 1987, 23, 571.
- An asthma model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate
- Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate (TDI)
- A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor
- Y. C. Lee, C. H. Song, H. B. Lee, J. L. Oh, Y. K. Rhee, H. S. Park, G. Y. Koh, J. Allergy Clin. Immunol. 2001, 108, 1021.
- Mesenchymal stem cell transfer suppresses airway remodeling in a toluene diisocyanate-induced murine asthma model
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