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Published TCIMAIL newest issue No.197
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CAS RN: 19387-91-8 | Product Number: T3058
Tinidazole
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€16.00
|
1 | ≥100 |
|
| 25G |
€54.00
|
1 | 39 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3058 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__8H__1__3N__3O__4S = 247.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 19387-91-8 |
| Reaxys Registry Number | 618182 |
| PubChem Substance ID | 253660404 |
| Merck Index (14) | 9447 |
| MDL Number | MFCD00057217 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 127.0 to 131.0 °C |
Properties (reference)
| Melting Point | 129 °C |
| Maximum Absorption Wavelength | 317(H2O) nm |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Acetone |
| Solubility (slightly sol. in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H341 : Suspected of causing genetic defects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| EC Number | 243-014-4 |
| RTECS# | NI6255000 |
Transport Information:
| HS Number | 2933299090 |
Application
Tinidazole: A Nitroimidazole Antiprotozoal Agent
Tinidazole, a structural analog of metronidazole, has been widely used as an antiprotozoal agent. It is used for treatment of trichomoniasis, giardiasis, amebiasis, and amebic liver abscess. It can also be used to treat Helicobacter pylori infection. Tinidazole dosage forms have been studied because of its poor water solubility. (The product is for research purpose only.)
References
- Tinidazole in anaerobic infections. A review of its antibacterial activity, pharmacological properties and therapeutic efficacy
- Tinidazole: a nitroimidazole antiprotozoal agent (a review)
- Tinidazole: from protozoa to Helicobacter pylori - the past, present and future of a nitroimidazole with peculiarities
- Novel application of hydrotropic solubilization in the spectrophotometric analysis of tinidazole in dosage form
- HPLC and LC-MS studies on stress degradation behavior of tinidazole and development of a validated specific stability-indicating HPLC assay method
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